Ectopic ACTH-secreting neuroendocrine tumor

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Ectopic ACTH syndrome caused by desmopressin-responsive thymic neuroendocrine tumor.

A 32-year-old Chinese woman with rapid weight gain and progressive edema was found to have typical Cushingoid features. Her endocrine data were consistent with a diagnosis of ACTH-dependent Cushing's syndrome. To differentiate ectopic ACTH syndrome (EAS) from Cushing's disease (CD), various dynamic endocrine and imaging tests were performed. Her ACTH response was negative to corticotropin-relea...

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An Ectopic ACTH Secreting Metastatic Parotid Tumour

A 60-year old woman presented with features of Cushing's syndrome (CS) secondary to an ectopic adrenocorticotropic hormone (ACTH) secreting metastatic parotid tumour 3 years after excision of the original tumour. She subsequently developed fatal intestinal perforation and unfortunately died despite best possible medical measures. Ectopic ACTH secretion accounts for 5-10% of all patients present...

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Sphenoidal Ectopic ACTH-secreting Pituitary Adenoma

INTRODUCTION Ectopic pituitary adenoma is defined as adenoma that occurs outside the sella without any continuity with the normal pituitary gland [1]. Since its description for the first time in 1909 by Erdheim in the vomero-sphenoidal region, about 75 cases have been reported in literature [2-12]. Sphenoid sinus followed by the suprasellar region remains the most common site for these adenomas...

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A rare case of an ACTH/CRH co-secreting midgut neuroendocrine tumor mimicking Cushing's disease

Ectopic ACTH/CRH co-secreting tumors are a very rare cause of Cushing's syndrome and only a few cases have been reported in the literature. Differentiating between Cushing's disease and ectopic Cushing's syndrome may be particularly difficult if predominant ectopic CRH secretion leads to pituitary corticotroph hyperplasia that may mimic Cushing's disease during dynamic testing with both dexamet...

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Mid-gut ACTH-secreting neuroendocrine tumor unmasked with 18F-dihydroxyphenylalanine-positron emission tomography

UNLABELLED Ectopic ACTH Cushing's syndrome (EAS) is often caused by neuroendocrine tumors (NETs) of lungs, pancreas, thymus, and other less frequent locations. Localizing the source of ACTH can be challenging. A 64-year-old man presented with rapidly progressing fatigue, muscular weakness, and dyspnea. He was in poor condition and showed facial redness, proximal amyotrophy, and bruises. Laborat...

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ژورنال

عنوان ژورنال: Orvosi Hetilap

سال: 2011

ISSN: 0030-6002,1788-6120

DOI: 10.1556/oh.2011.29053